The run raises money for bran cancer research and children's programs at Memorial Hermann Hospital.
It's held annually in honor of the memory of Dr. Marnie Rose. Brain cancer killed the local pediatrician in 2002. Prior to her passing, she continued to allow cameras from ABC's Houston Medical to watch her journey through chemotherapy.
Marnie's fight inspired her mother, Lanie Rose, to start a foundation in her name that benefits research and provides support for affected families.
In its inaugural year, not a single brain cancer survivor participated in the run and walk. Last year, there were 71 among the 4,800 who chose to participate. It's a testament to the efforts of this annual event, which hopes one day there won't be a need for a walk or run because there will be a cure.
"It means so much to us that Marnie can be remembered for helping others," Lanie Rose said at last year's event. "Not just for the fact that she died too soon."
If you're interested in taking part in this year's Run for the Rose or donating, you can sign up here.