Firefighters were called out to the home on FM 1462 near Highway 288 around 11pm in Brazoria County. When they arrived, 40 foot flames were already shooting from the home.
Since the home is located on a private airfield, firefighters are still working to figure out if a plane might have been inside.
"We believe there's a hangar attached. This is a private airfield and we haven't been able to get into the house yet to determine what's all in the house, what's on the inside," said Asst. Chief Kendall Hunting with the Alvin Fire Department.
Authorities say there were people inside the home at the time of the fire, but they made it out safely.