The presidential duo will speak at a high-dollar fundraiser at a private home, then headline a gala at the Waldorf Astoria hotel. Obama and Clinton will end the night at an event dubbed "Barack on Broadway" at the New Amsterdam Theatre.
Monday's trip is Obama's first of two fundraising blitzes in New York over the next two weeks. He will return to Manhattan next week for a fundraiser at the home of actress Sarah Jessica Parker.
Obama is seeking to persuade voters that he is still the right steward for the economy following a dismal jobs report out last week that showed an uptick in the unemployment rate.