Lightning struck a tree next to a home in Grangerland around 2:30pm and flames soon engulfed the house, officials said.
It happened in the 17800 block of Springfield Drive.
Caney Creek Fire Department, River Plantation Fire Department and New Caney Fire Department responded.
By the time firefighters arrived, the sigle-story, wood-frame house was heavily involved in fire. A shed on one side had already burned to the ground and the flames had spread to the house and woods.
Officials said the wooded area was quickly contained and crews worked to stop the blaze from advancing through the house.
Most of the structure was lost.
The homeowner was not home at the time of the fire. No injuries were reported.