Doug Plude was accused of poisoning 28-year-old Genell Plude with migraine medicine, drowning her in the toilet at their Land O'Lakes home and trying to make it look like a suicide.
The 43-year-old pleaded guilty to first-degree reckless homicide as part of a plea deal this fall.
Plude initially was convicted of first-degree intentional homicide in 2002, and served five years. That conviction was overturned because an expert witness had exaggerated his credentials.
Plude received credit for time served, so he'll serve a little more than 19 years.
In court Wednesday, Plude reasserted that his wife killed herself with prescription drugs and that he was sorry it happened.