Paramedics and campus safety officers responded, but it's unclear if Nye was treated.
USC senior Tristan Camacho says Nye collapsed in mid-sentence at the podium. About 10 seconds later, she says he was conscious and asked the audience how long he was out.
Nye told the audience a similar thing happened to him earlier in the day.
Nye assistant Christine Sposari didn't immediately respond to an e-mail request for information sent early Wednesday.