Game 3 on Friday night might be their only chance to turn things around.
Philip Ernst studies, dissects, and analyzes numbers all the time. He's an associate professor of statistics at Rice University.
RELATED: Still Clutch City: Astros may need to tap into their inner 1994 Rockets for comeback
He said while the odds aren't great, there is hope for fans. According to Ernst, models put the Astros' chances of becoming champions again at 19 to 27 percent.
"Unfortunately, the odds are not in their favor right now," he admitted. "There's a 26 percent chance, according to the most simple model, that they will win the World Series."
Though, he says relax, 'Stros fans.
"But there is good news to look forward to if they win Game 3. The Vegas odds go up to about 41 percent of them winning the World Series. If the Astros win both Game 3 and Game 4, then they have a 63 percent chance of winning the World Series. If they win Game 3, 4, and 5, then they're already at a 86 percent chance of winning the World Series. There's definitely hope," he said.
Bottom line. The Astros need a win Friday in Washington.
OUCH: World Series trophy presentation took place in DC before Game 3
Keep the faith, Astros fans: Church sign hits home run everywhere
Follow Steve Campion on Twitter and Facebook.