"Tyler Perry's Madea's Big Happy Family" debuted a close second with $25.8 million, another solid opening for writer-director Perry, who also stars as boisterous, opinionated grandma Madea.
Reese Witherspoon and Robert Pattinson's circus romance "Water for Elephants" premiered in third-place with $17.5 million.
A love-bird story centered on rare parrots, "Rio" raised its domestic total to $81.3 million. The movie has taken in $204.7 million more overseas, for a worldwide haul of $286 million.