The driver did manage to get out, but authorities say he suffered severe burns to least 80 percent of his body. No other vehicles were involved.
TxDOT officials will have to come out and test the integrity of the freeway, but for now the clean up continues.
"Our concern is trying to get the freeway reopened. We got about 100 gallons of diesel fuel spilled and now it's starting to run to the ground below us, so we are going to contain it first and then clean it up," said T.J. Slagle with the Houston Fire Department.
About 100 gallons of diesel fuel spilled and fell to the ground and the Environmental Protective Agency will be out to assess if there are any environmental issues.
The inbound lanes of the Katy Freeway near Houston Avenue were closed for several hours. All lanes reopened just after 8am.