The best of the newcomers was the rock 'n' roll comedy "Get Him to the Greek," which debuted at No. 2 with $17.4 million. Opening at No. 3 was the action comedy "Killers" with $16.1 million.
The overall box office tumbled compared with last year's. The weekend after Memorial Day a year ago, the blockbuster "Up" premiered with $68.1 million.
That was more than the total for this weekend's four new wide releases -- which included the family comedy "Marmaduke" at $11.3 million and the horror tale "Splice" at $7.5 million.