It happened just before 8pm at an apartment complex in the 1500 block of Big Bend Drive at Long Point Road.
According to Houston Police Department, a 52-year-old man was found shot to death in an apartment.
Investigators identified the suspect as his wife and said she was taken into custody. They said the couple was arguing at their apartment when the wife took out a gun and pulled the trigger.
Authorities are questioning witnesses to find out additional details. There is no word yet on possible charges.