Mrs. Reid was in serious condition, but Reid aides said she was not expected to require surgery.
"Mrs. Reid has a broken nose, broken back and broken neck," Reid spokesman Jim Manley said in a statement. "Lana has a neck injury and facial lacerations." Manley said Mrs. Reid could feel her extremities.
Virginia State Police said Mrs. Reid and her daughter were traveling northbound on I-95 in stop-and-go traffic when their Honda Odyssey was rear-ended by a tractor-trailer loaded with rolls of plastic. The impact forced the Reid family's minivan to rear-end a Jeep Grand Cherokee, which in turn struck a Chevrolet Cobalt.
The driver of the tractor-trailer, Alan W. Snader, 59, of Ohio, was charged with reckless driving, police said. He was not injured. All involved were wearing seat belts, police said.
Reid, D-Nev., went to the hospital after being notified of the accident and returned to Capitol Hill for a meeting with White House Chief of Staff Rahm Emanuel and House Speaker Nancy Pelosi on efforts to pass health care legislation. He went back to the hospital Thursday evening.
Reid, 70, met Landra while they were attending Basic High School in Henderson, Nev. They were married in 1959. Lana was born two years later. The couple also have four sons: Rory, Leif, Josh and Key. Lana Barringer has three children.