Rob Lowe to leave `Brothers & Sisters'

Actor Rob Lowe attends a press conference for the film 'Invention of Lying' during the Toronto International Film Festival on Monday, Sept. 14, 2009 in Toronto. (AP Photo/Evan Agostini)

January 22, 2010 1:53:24 PM PST
Rob Lowe wants a smaller TV family. His publicist says the actor is leaving ABC's "Brothers & Sisters" at the end of the season. Lowe plays Sen. Robert McCallister on the drama, which also stars Calista Flockhart, Sally Field and Rachel Griffiths.

This isn't the first time Lowe has walked away from an ensemble gig. He left "The West Wing" after four seasons and went on to star in his own show, "The Lyon's Den."