It happened around 9:30pm Friday on Lemon Tree Lane near Vogel Road.
Police say the gunman was waiting in an abandoned house until the homeowner pulled into his garage. That's when the gunman jumped over a fence and ambushed the man.
The homeowner was shot once in the stomach.
Police believe the suspect was trying to rob the man, but it is unclear whether he got away with anything. Police haven't said if the victim was targeted or if it was a random attack.
The gunman remains on the loose and the homeowner is in the hospital, expected to survive.
Anyone with information on this incident is urged to call HPD or Crime Stoppers at 713-222-TIPS.