Houston's Mayor Sylvester Turner and Congresswoman Sheila Jackson Lee are there to kick off the United Flight.
The flight marks a milestone.
For the first time in more than 50 years people are now flying commercially to Cuba.
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Ten U.S.-based airlines have been approved to schedule services to Cuba including: Alaska Airlines, American Airlines, Delta Air Lines, Frontier, JetBlue, Silver Airways, Southwest, Spirit, Sun Country and United.
You still cannot travel to Cuba as a tourist which means no special beach vacations.
In order to go, you must verify that you meet one of the twelve pre-approved categories allowed by the U.S. government.
The approved list includes: family visits and research, journalistic, religious and educational activities.
The most common form of travel is people-to-people. This is basically a term for a cultural experience to learn about the Cuban community.
United will be the only airline offering nonstop service from IAH and will fly out every Saturday.