The victim was reportedly riding on the unimproved shoulder north of the roadway when a car failed to drive in a single lane and hit the bicyclist.
Investigators described the suspect vehicle as a dark blue Ford or Dodge pickup. The driver did not stop to render aid to the victim, who died at the scene, police said.
A man in a wheelchair was killed in a hit-and-run crash on Friday night, and Houston police said they're looking for the driver.
Police said the 22-year-old was taken to the hospital after being hit by a truck driver who took off Thursday morning.
A woman whose family members say was on her usual morning walk for coffee was killed in a hit-and-run crash early Tuesday in Pasadena.
The former U.S. attorney for the Southern District of Texas is now facing felony charges. Investigators say she left the scene of a crash in Houston that injured another driver.