Hartman says the jobs being eliminated do not involve direct patient care.
Seton began notifying managers Feb. 10 about the cuts. Hartman says Seton's goal is to trim its budget by 5 percent.
Hartman says Seton is the largest hospital system in central Texas, with a network of 31 facilities, and provided $281 million in charity care during 2008.
Seton, with about 11,500 employees, serves an 11-county population of 1.8 million.