The accident happened around 5:30pm on Highway 225 near Highway 146.
La Porte police say one car was towing another when the strap disconnected and the two vehicles collided. Three other cars then crashed in a chain reaction, an a Goose Creek ISD bus then rear-ended the last car.
Sixteen players from the Sterling High School girl's soccer team and their coach were aboard the bus, but none of them were injured.
Some of the other people involved in the wreck suffered injures but weren't severe enough to require hospital care.