The flyover route proceeded over the city of Houston, parts of Sugar Land, Katy, and Harris County and took the fleet toward Galveston County before heading out over the Gulf of Mexico.
WATCH: Viewer and ABC13 staff video of the Blue Angels flyover in the Houston area
The fly over was even more special for some Houston-area residents, as a Kingwood native is one of the pilots.
Major Frank Zastoupil is in his first season flying with the Blue Angels. He's also the first F-35 pilot to do so.
WATCH: Kingwood native will fly over Houston with the Blue Angels
The flyover was a show of support for health care workers, first responders, and other essential personnel on the frontlines of the COVID-19 pandemic.
Last week, the Blue Angels joined the Air Force Thunderbirds in a flyover of the Philadelphia and New York City regions.
The Blue Angels released video showing the view from inside the cockpit as the jets took flight. The skyscrapers from the Philadelphia and New York skylines could be seen from outside the cockpit window as the Blue Angels flew in formation.
"We are incredibly honored to have the opportunity to salute those working on the frontline of the COVID-19 response, we are in awe of your strength and resilience," said Navy Cmdr. Brian Kesselring, U.S. Navy Blue Angels commanding officer and flight leader. "Thank you to all of those in essential industries keeping our nation moving forward. We will get through this. We are all in this together."
The Blue Angels also flew over Dallas/Fort Worth on Wednesday.
Later in the week, you'll be able to see another fabulous fleet.
The Lone Star Flight Museum plans to fly nearly 30 rare and historic aircraft across the area to commemorate the end of World War II, according to a statement on the museum's website. That event will happen Friday.
Dozens of vintage aircraft to fly over Houston on Friday