Harris County Sheriff's Office deputies say the motorcyclist was speeding down F.M. 1960 around 9pm Saturday, weaving in and out of traffic.
That's when he hit the back of what witnesses say was a dark-colored sedan.
Investigators say the car left the scene for unknown reasons.
The biker was taken to Northwest Medical Center where he later died.
Authorities are still looking for the driver of the car. They are investigating whether that person will face charges for failing to stop and render aid.
Anyone with information can call HCSO or Crime Stoppers at 713-222-TIPS.