It happened just before 2:30am in the 200 block of the 610 North Loop East westbound just before Interstate 45.
According to police, the woman lost control of her gray Chevrolet Impala and slammed into a concrete barrier.
"Our witness said she was just driving along and lost control, so we don't know what the cause of the initial accident actually was," HPD Sgt. J.R. Roberts said.
After the crash, the woman got out to assess the damage and was walking the main lanes of the North Loop.
As a witness was reportedly yelling at the woman to get out of the roadway and back into her car, a black Kia sedan crashed into the disabled vehicle.
The Impala then hit the woman, who was thrown into the air and pronounced dead at the scene. Her name has not been released. Police are awaiting toxicology reports to determine if she was in any way impaired before she crashed.
Police identified the driver of the Kia as Richard Arroyo, 24. He was arrested on suspicion of driving while intoxicated. Charges are pending.
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