2026 NFL schedule release: Odds for every Week 1 game, other highlights

The complete 2026 NFL schedule has been released, and odds are already available for Week 1 and several other high-profile games.

The Seattle Seahawks and New England Patriots will meet in a Super Bowl rematch in the NFL's season opener on Wednesday, Sept. 9. The defending champion Seahawks opened as 3.5-point home favorites.

The international series gets going Thursday, Sept. 10, with an NFC West matchup between theLos Angeles Rams-- the current favorites to win the Super Bowl-- and rivalSan Francisco 49ersin Melbourne, Australia.

The largest spread of Week 1 belongs to the Los Angeles Chargers, who are favored by 11.5 points over the Arizona Cardinals. The Chargers are the only double-digit favorite. Nine games have spreads of a field goal or less.

The highest points total in Week 1 is the Tampa Bay Buccaneers-Cincinnati Bengals matchup (50.5).

Here's a look at the early odds for every Week 1 game, as well as other highlights on the schedule that already have spreads.

Wednesday, Sept. 9

Moneyline: Seahawks -192, Patriots +160

Total:44.5 points

Thursday, Sept. 10

Moneyline: Rams -148, 49ers +124

Total:48.5 points

Sunday, Sept. 13

Moneyline: Bears -135, Panthers +114

Total:44.5 points

Moneyline: Bengals -198, Buccaneers +164

Total:50.5 points

Checkout all 32 teams' Super Bowl odds, win total projections and more.

Moneyline: Ravens -185, Colts +154

Total:49.5 points

Moneyline: Bills -112, Texans -108

Total:45.5 points

Moneyline: Lions -325, Saints +260

Total:48.5 points

Moneyline: Titans -170, Jets +142

Total:39.5 points

Moneyline: Steelers -175, Falcons +145

Total:42.5 points

Moneyline: Jaguars -290, Browns +235

Total:40.5 points

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Moneyline: Chargers -625, Cardinals +455

Total:45.5 points

Moneyline: Packers -125, Vikings +105

Total:44.5 points

Moneyline: Raiders -175, Dolphins +145

Total:41.5 points

Moneyline: Eagles -238, Commanders +195

Total:46.5 points

Moneyline:Cowboys -130, Giants +110

Total:48.5 points

Monday, Sept. 14

Moneyline:Chiefs -155, Broncos +130

Total:42.5 points

Other highlighted games with odds available

"Thursday Night Football"

Sept. 17:Detroit Lions at Buffalo Bills (-3, 52.5),8:15 p.m. ET (Prime Video)

(First game at the new Highmark Stadium)

Thanksgiving Eve

Green Bay Packers at Los Angeles Rams(-3.5, 49.5), 8 p.m. ET (Netflix)

Thanksgiving Day

Chicago Bears atDetroit Lions (-2.5, 51.5), 1 p.m. ET (CBS)

Philadelphia Eagles (-1.5, 49.5) at Dallas Cowboys, 4:30 p.m. ET (FOX)

Kansas City Chiefs at Buffalo Bills (-2.5, 49.5), 8:20 p.m. ET (NBC)

Christmas Day

Green Bay Packers at Chicago Bears (-1.5, 47.5), 1 p.m. ET (Netflix)

Los Angeles Rams at Seattle Seahawks (-1.5, 47.5), 8:15 p.m. ET (FOX)

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