SkyEye captured at least five vehicles involved in the crash, including one being pinned against a wall by a big rig.
It's not immediately known if anyone was killed or injured.
TxDOT said at least one lane of traffic was allowed open as a hazmat cleanup got underway.
A left lane has opened up on I-45 NB at Airtex. Hazmat clean up is underway. Expect closure to be in place for an hour or more. https://t.co/78WSDemNLD
— TxDOT- HOU District (@TxDOTHouston) May 7, 2020
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