Investigators searching under a tarp in the yard recovered the body of a 28-year-old man outside a home on Wyoming Street on the city's east side.
The victim and suspect were not immediately identified.
Neighbors told several San Antonio media outlets that a party at the home had begun Tuesday night and lasted into Wednesday morning.
The victim and suspect are believed to have become involved in an altercation around 9 a.m.
The incident marks San Antonio's first homicide of 2014.
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