The guards were not injured. They called the Houston Police Department and an officer responded.
As the guards were telling the officer their story, the suspect drove by in a maroon Lincoln.
The officer chased the suspect about a mile until he lost control of the Lincoln in the 1600 block of Dunaway near Strick.
Police said the suspect got out of his car, wielding a rifle that he pointed at the officer.
The officer told the man to drop the weapon, but the suspect refused. Officials said the police officer fired at the suspect, who then fled into a nearby wooded area.
It is unknown if the suspect was struck.
According to investigators, two other people in the Lincoln were detained for questioning.
The incident is being investigated by HPD's homicide and internal affairs divisions, as well as the Harris County District Attorney's office, which is routine procedure for officer-involved shootings.
Anyone with information that may be helpful to this investigation is urged to call Crime Stoppers at 713-222-TIPS. All tipsters remain anonymous.