Investigators said 28-year-old Jeremy Jones has been charged with capital murder in the deaths of 31-year-old Gary Rusher and 33-year-old Christopher Beatty.
Meantime, Harvey Jones, 34, is charged with aggravated assault with a deadly weapon.
Residents deal with tragic loss in Haverstock Hill shooting
Both men are on the run, and homicide investigators said they need the public's help finding them.
The violent shooting happened Sunday night at the Haverstock Hills Apartments on Aldine Bender.
ORIGINAL REPORT: 2 dead, 4 injured in shooting at NE Harris Co. apartment complex
Investigators said an argument turned very violent when a man got out of the car, grabbed a gun from the trunk and fired into the group.
Jeremy Jones allegedly fired about 18 rounds from a semi-automatic weapon, hitting six people. Two of those victims died, while four others were rushed to the hospital. Three of the victims were identified as siblings Brandy, Isaiah and Wayne Rusher.
Harvey Jones, meantime, is accused of pointing the gun at the victims.
Anyone with information on their whereabouts should call the Harris County Sheriff's Office Homicide Unit at 713-274-9100.
You can also make an anonymous tip by calling Crime Stoppers at 713-222-TIPS, or filing your tip on their website, www.Crime-Stoppers.org.
RELATED: Former 'ANTM' contestant among 4 injured during shooting in Houston
Report a typo to the ABC13 digital staff