It happened some time before 2 a.m. in the westbound lanes just west of Lockwood Drive.
Officers responded to a report of a pothole in the road and were waiting for TxDOT to arrive to make repairs when a car slammed into one of the HPD cruisers, police said.
One officer suffered cuts to the head and was taken to a hospital. Their condition wasn't immediately known Saturday morning.
The driver of the other vehicle was also transported to a hospital with minor injuries, HPD said. Investigators do not believe impairment was a factor in the crash.
The crash was the latest in a series of crashes involving police vehicles over the past month.
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