Bryant's Ikenna Ndugba, thinking his team had the lead with less than four seconds to play in Providence, Rhode Island, dribbled the ball circuitously to half court and heaved it overhead.
One problem: Bryant was trailing Brown by a point.
With the lead quickly changing hands twice in the waning seconds Monday, Ndugba, a freshman from Boston,lost track of the score after alayup gave the Ivy League Bears the final 91-90 lead.
Ndugba, looking for a high-five from a teammate after releasing the ball into the air, was instead met with confusion. Brown players mobbed the court in celebration.
Joshua Howard scored 18 points, and Tavon Blackmon's last-second layup helped Brown improve to 3-4.
Blackmon had nine points and eight assists while committing just one turnover. His game winner came moments after Nisre Zouzoua buried a 3 to give Bryant, which plays in the Northeast Conference, a 90-89 lead with 12 seconds left.
Steven Spiethmade back-to-back layups to give Brown an 89-83 lead with 2:47 to play.
Ndugba and Marcell Pettway made layups to bring Bryant (2-5) within two with 1:02 left.
Speith scored 16 and had nine assists, JR Hobbie had 15 points, and Travis Fuller scored 11 for the Bears.
Brown, which had a 43-39 lead at halftime, led 50-41 early in the second half on Corey Daugherty's 3-pointer.
Zouzoua scored a career-high 31 points and had six rebounds and five assists for Bryant. Adam Grant added 20 points, and Bosko Kostur had 16 points and seven rebounds.
Information from The Associated Press was used in this report.