Houston Police Department officers responded to the shooting at Oak Club on Southmore Boulevard near Live Oak at about 2 a.m.
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When officers arrived, they found a large chaotic crowd with several "disturbances" happening, police said.
Investigators said there was an argument inside the club between a man and woman that ended up spilling outside.
Police said they don't know much about the suspects but believe multiple people fired shots.
One man, between 20 and 30 years old, was shot and killed at the scene, according to police.
Two other men and a woman were transported to Ben Taub Hospital in stable condition.
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HPD said both men were shot in the leg area, and the woman was shot in her neck.
Investigators said they were able to interview some witnesses but that a lot of people left the scene without speaking to police.
Surveillance video obtained by ABC13 shows a chaotic crowd fighting and running away as shots were being fired.
A nearby business owner who spent the day making repairs said she wants to see something done about the crime in this area.
"We still have to open for business even with the chaos," Cupcake Kitchen Houston owner, Patrice Farooq, said. "My concern is, what's being done about (the shooting)?"
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Farooq woke up early Saturday morning to call her alarm company after the shooting happened outside of her bakery.
Video captures at least one person pulling out a gun, although it did not capture anyone getting shot.
Police are still working to track down several suspects.
"We do know we have multiple shooters," HPD Commander Caroleta Johnson said.
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