Harris County Sheriff's Office deputies said at about 8:30 p.m., it was reported that a man driving a slingshot was going the wrong way on FM 529 near N. Eldridge Parkway.
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The man was traveling westbound in the eastbound lanes when he then crashed into four other vehicles, according to deputies.
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HCSO said the man was transported via Life Flight in critical condition.
The other parties involved in the crash remained at the scene and did not report any injuries.
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Authorities are investigating to see if alcohol played a factor in the crash.