The call came in just before 1 p.m. on Friday.
Police said officers were told several people in a white Cadillac were firing shots along Will Clayton Parkway.
Details on the exact model of the vehicle wasn't immediately released.
It's also unclear if anyone was shot.
Police said two people are in custody and a third person, who they believe is involved, remains on the run. A description of that person, however, was not released.
Note: The video above is a breakdown of what to do when submitting a tip to Crime Stoppers of Houston.
This is a developing story. This article will be updated as more information becomes available.