The Harris County Sheriff's Office said the incident unfolded at about 7 p.m. on Tuesday at a home along Diantha Street.
HCSO said the woman called 911, saying she shot her husband during an argument that had turned physical. The man, identified as Qualin Dorsey, reportedly died at the scene from at least one gunshot wound.
Deputies said the couple's son was at the home at the time and was going to be interviewed by investigators to try to piece together what happened.
The sheriff's office said the woman was not arrested Tuesday night, and instead, a grand jury will determine if charges should be filed in this case.
If you need help getting out of a domestic violence situation, call the Houston Area Women's Center 24/7 hotline at 713-528-2121 or call AVDA at 713-224-9911. You can also click here to chat with an advocate online. If you are deaf or hard of hearing and need help, call 713-528-3625.