The crash happened in the outbound lanes just before 9 a.m. near the West Loop.
ABC13 SkyEye flew over the scenes and saw traffic backed up on the roadway. A truck was also seen smashed beneath the truck's rig near the shoulder.
Officials did not say what caused the crash or if there were any injuries.
That area will remain closed until crews clear it.
ABC13 has real-time traffic data to help you navigate Houston's roads and avoid traffic delays.
[Ads /]
Sign up for traffic alerts that are sent straight to your phone through our ABC13 app. Manage your notifications from the settings tab.
Live traffic map