Houston TranStar reported the incident at I-10 Katy Freeway eastbound before Barker Cypress Road just before 6 a.m.
TranStar cameras show crews working to clean up what appears to be a lost load of gravel.
Police are blocking the right lanes as the cleanup continues.
It's unclear what led to the incident or if anyone was injured.
ABC13 has real-time traffic data to help you navigate Houston's roads and avoid traffic delays.
[Ads /]
Sign up for traffic alerts that are sent straight to your phone through our ABC13 app. Manage your notifications from the settings tab.
Live traffic map