Firefighters were called at about 10:30 a.m. to 6060 Hooten Road at Southwest Freeway, the department said.
SkyEye was at the scene and saw someone was being taken away on a stretcher.
The department said the fire is not a two-alarm fire at this time. A two-alarm fire requires help from other departments, like additional pumpers and ladder trucks.
No firefighters were reportedly injured.
Individuals are being urged to avoid the area while firefighters perform an offensive attack, according to the tweet.