The deputy was assisting at the crash scene along Highway 99 and Cumberland when he was run over, Sheriff Ed Gonzalez said on X.
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Gonzalez said the deputy had been seriously injured and flown to the hospital, where he later died.
SEE MORE: Tributes pour in for Harris Co. deputy killed on Grand Parkway
"It is a sad day in Harris County as we mourn the loss of a deputy who died in the line of duty. We share our sorrow with his family & his extended family, the women & men who put their lives on the line every day to keep our county safe," Gonzalez said.
The deputy was identified by the sheriff's office as 50-year-old John H. Coddou, who had served with HCSO since 2003.
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During the commissioner's court session on Tuesday morning, Harris County Judge Hidalgo and Commissioner Adrian Garcia asked for a moment of silence.
The crash caused the highway to shut down in both directions, but it has since been reopened.
SEE MORE: Who was John Coddou, the Harris County deputy killed in a crash on Grand Parkway?
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