The crash happened at about 4:57 a.m. on Saturday near Bellaire Boulevard.
The lanes were reopened around 9:19 a.m.
Houston police started to direct incoming traffic towards the Fondren Road exit.
According to police, the crash was fatal, but did not give any further details.
ABC13 has real-time traffic data to help you navigate Houston's roads and avoid traffic delays.
Sign up for traffic alerts that are sent straight to your phone through our ABC13 app. Manage your notifications from the settings tab.
Live traffic map
Do you hate Houston traffic as much as we do? Join the club!