The accident happened Tuesday at about 11:45 a.m. on US-290 near Antoine.
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The video shows an 18-wheeler veer into another lane, striking one car and sending it across the freeway out of control.
That vehicle struck another vehicle and rolled over three times on the freeway.
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The Houston Police Department said one person was transported to the hospital.
The investigation into the accident is ongoing.
Truck ran red light near 290 and killed 79-year-old passenger: Police
Truck ran red light and killed 79-year-old: Police
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