Police say two people were inside a Dodge Durango when the crash happened at around 2:30 a.m. Friday in the 300 block of Main Street near Highway 3.
According to police, the train engineer did not realize the SUV was wedged under before moving. An officer driving next to the tracks saw the wreckage and flagged the train to stop.
One of two people in the SUV became trapped at the scene. A man and a woman were flown from the scene to UTMB hospital in Galveston. The man is in serious condition, while authorities consider the woman's injuries as non-life threatening.
Police are looking at alcohol as a factor in the crash. Charges are pending.
Stay with Eyewitness News for updates on this developing story.
Report a typo to the ABC13 staff