Source: Calf injury expected to sideline Texans' DeAndre Hopkins

HOUSTON -- Houston Texans wide receiver DeAndre Hopkins is not expected to play Sunday against the Indianapolis Colts, a source confirmed to ESPN.

The news was first reported by The Houston Chronicle.

Hopkins has been on the injury report this week with a calf injury and has not practiced. The wide receiver has not missed a game in his five-year NFL career and has caught a pass in each of those 79 games.

Despite playing with four different quarterbacks -- Tom Savage, Deshaun Watson, T.J. Yates and Taylor Heinicke -- this season, Hopkins leads the NFL with 13 receiving touchdowns. He will finish the year with 96 catches for 1,378 yards, just shy of career highs he set in 2015.