George Springer also homered to help Dallas Keuchel coast in Houston's second straight romp by the exact same score.
The Astros will go for a sweep in the best-of-five matchup Sunday at Fenway Park.
A day after Altuve hit three home runs in the playoff opener, he got things going with a two-out single in the first inning off Drew Pomeranz. Correa, who went 0 for 4 on Thursday, made it 2-0 when he launched a towering shot onto the train tracks atop left field.
Keuchel pitched into the sixth, allowing one run and three hits while striking out seven.
The Associated Press contributed to this report.
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