The victim has been identified as Alyssa Elsman. She was among 23 people struck by a speeding car driven up the sidewalk on Seventh Avenue just before noon.
Elsman was with her 13-year-old sister, who was also injured in the crash.
Alyssa Elsman graduated high school last summer.
"She was a terrific young lady... and we will really miss her," said Eric Alburtus, principal at Portage Central High School.
PHOTOS: Car plows into crowd in Times Square
Police said the driver was high on drugs - possibly synthetic marijuana (K2) when he made the turn up Seventh Avenue from 42nd Street and drove three blocks before striking a metal pole.
RELATED: What we know about the driver