Derren Sorells, 22, and Darwin Sorells, 26, were both arrested on Sunday, according to a tweet from Chicago Police Communications Director Anthony Guglielmi.
Aldridge, 32, was pushing a stroller when she was hit by a stray bullet Friday afternoon in Chicago's Parkway Gardens neighborhood. Investigators said Aldridge was an innocent bystander and not the intended target.
Wade was not in Chicago on Friday, but joined an ESPN roundtable on Thursday about violence in Chicago. He tweeted about his cousin's death Friday night.
Wade tweeted again on Saturday, saying, "RIP Nykea Aldridge... #EnoughIsEnough."
Police said Aldridge had just left the Dulles School of Excellence around 3:30 p.m. in the 6300-block of South Calumet when two men approached another man in the vicinity and opened fire.
Aldridge -- who was walking home after enrolling her children in school -- was struck in the head and arm and taken to Stroger Hospital, where she was pronounced dead.