It happened around 3:30 a.m. in the 7100 block of Eppes St. in southeast Houston.
The victim, believed to be a man in his 20s, was with his father inside the home when someone shot him in the abdomen, according to Houston police homicide investigators.
The man was taken to a hospital, where he died.
The shooter got away, police said.
Investigators were still working Sunday to find out what exactly happened.
The victim's identity wasn't immediately released.
Shooting: 7100 Eppes. Male shot in abdomen during home invasion, transported to area hospital. #hounews CC8— Houston Police (@houstonpolice) September 27, 2020