"Why would you do us like this? Dedicated and die-hard fans! We DO NOT deserve this!" Courtney Williams wrote in an open letter to 'Grey's' show runner Shonda Rhimes.
"You do not have someone survive a mass murderer, a plane crash, A FREAKING PLANE CRASH, AND A crushed hand, as a neurosurgeon...just to kill them off on a BEAUTIFUL DAY!! Seriously? SERIOUSLY SHONDA?! SERIOUSLY MS. RHIMES!?!?!?!?!"
PHOTOS: 'Grey's Anatomy' cast 10 years after show premiere
More than 50,000 people have already signed Williams' change.org petition, commenting that they hope the episode will end up being a dream sequence or threatening to boycott the show over the character's unexpected death.
Patrick Dempsey, who played Dr. Derek Shepherd for the past decade, told EW that he was not surprised to learn he was being written off the show.
"It was just a natural progression with the way the story was unfolding," he said. "It was like, 'Okay!' This was obviously the right time."
'Grey's' fans took to social media last week to express the trauma they felt by the death of the beloved character.
Can I sue a fictional hospital for wrongful death? #GreysAnatomy— Casey Goldstein (@CaseyGoldstein) April 24, 2015
ABC issued a statement saying in part, "The devotion of Grey's fans throughout the years has been a testament to the creative mind of Shonda Rhimes and Dempsey's talent. "McDreamy" will be greatly missed and we wish Patrick the very best in his future endeavors."
The season finale of Grey's Anatomy airs May 14 on ABC.
ABC is the parent company of this station.