The survey, released Wednesday from NPR, Robert Wood Johnson Foundation, and Harvard's T.H. Chan School of Public Health, explores COVID-19's impact on households in the nation's four largest cities: New York City, Los Angeles, Chicago and Houston.
At least half the households in all four cities report facing serious financial problems in the midst, and because, of the pandemic. The study, conducted July 1 - Aug. 3, found many households' savings are drained. It also showed many are struggling to pay rent, pay major bills and ensuring the household has enough to eat. More than half are reporting serious problems caring for their children.
RELATED: Despite CDC eviction ban, couple with 7 children forced to move a day before school starts
In nearly every case, the impact hits disproportionately harder among Black and Latinx households, and households with incomes below $100,000. It underscores a blow already sustained by those groups amid the pandemic.
Economic fallout from COVID-19 has slammed communities of color, more harshly affected by record unemployment numbers now weathered by the nation. Those same groups, increasing evidence shows, are already disproportionately affected by the virus itself.
"These communities remain so vulnerable and in some serious trouble," Dr. Robert Blendon, professor of Public Health and Political Analysis at the Harvard T.H. Chan School of Public Health, told ABC News. "We hear those PSA's that say - we're all in this together. It turns out, that's not correct: what we see in the survey is, if you earn less, every increment down, you have more troubles. And if you're Latino, or Black, your problems are dramatically more serious."
MORE FROM ABC News on the survey
57 percent of the people polled in Houston said they suffered some sort of job loss or furlough compared to 46 percent nationally.
The information was gathered between July and early August prior to federal coronavirus support programs expiring.
"It's not a pretty picture," Dr. Julie Morita, executive vice president of the Robert Wood Johnson Foundation, told ABC News. "People struggling to make ends meet and struggling to meet the basics - basically living on the edge. And then what pandemic does - is just push them over the edge."
"This pandemic has revealed glaring problems in the nation's healthcare system," said Dr. Richard Besser, president and CEO of the Robert Wood Johnson Foundation. "At a time when a significant number of people need health care most, many cannot get it. We need to be able to provide safe, affordable health care for people with Covid-19 as well as for the many with chronic medical conditions so rampant in America. It is unacceptable that in a wealthy nation like ours factors such as income or race play such a big role in health care access."
Now with the insight their survey yields, Morita said, they hope to inform policy.
"I'm hopeful this will motivate us to move forward with policies that will really address the structural barriers that have been out there for so long," Morita said. "What can we do to help people keep off that edge, to a better living baseline when the next pandemic comes - because we know there will be another one - and we can prevent these inequities from occurring again."
ABC News' Eric Strauss contributed to this report.