According to the Harris County Precinct 8 Constable's Office, a Mazda car was traveling east on NASA Parkway when the driver made a left turn near Kings Park Lane into an apartment complex, failing to yield the right of way to oncoming traffic.
Deputies said a westbound Ford F-250 pickup was unable to stop. The truck hit the Mazda, killing the car's driver at the scene.
Two passengers in the Mazda were taken by Life Flight to an area hospital with unknown injuries.
Officials said the driver of the truck was not hurt. His truck was not even damaged.
"The airbag in the F-250 did not even deploy. We don't think speed was a factor, just simply failure to give right of way," Pct. 8 Capt. Jeff Lamar said.
Just across the street stands a memorial for another accident.
"They were coming across NASA and they got run over," nearby resident Jessica Gough said of the victim.
Gough said she has seen so many accidents at the intersection that she now avoids the area.
"I don't like driving on NASA Road One anymore. It's a danger," she said.
Others plan to petition the city for a traffic light at the intersection.
"I've been here nine years and that is a very, very dangerous intersection. People are always doing NASCAR turns," Diane Hillis said.That would have been prevented if there was a traffic light here."