The Cincinnati Enquirer reports the pursuit began early Tuesday after a store manager reported the girls stole potato chips and other items and took off in a car. An officer who responded saw a similar vehicle pass by and unsuccessfully tried to pull it over, leading to the pursuit.
Police say the 16-year-old driver and two passengers, a 12-year-old and a 14-year-old, were taken to a hospital and charged with theft. The youngest is in critical condition.
Two other teens were unhurt and cited for curfew violations.
Police were investigating whether the officer followed proper procedure.