It happened around 7:30am on Lockwood in the Second Ward.
According to police, a man in his 40s was collecting cans on the side of the Lockwood when a southbound SUV went up on the curb and struck him.
The SUV fled the scene and was found a short time later on Hoffman near Colfax.
Police have someone in custody, but it's unclear if it is a suspect.
The pedestrian was taken to Ben Taub General Hospital in unknown condition.
Please stay with Eyewitness News and abc13.com for updates as they become available.