Firefighters were called to the 1300 block of West Harris near the Houston-Pasadena border. When they arrived around 5:30am, they found the home fully engulfed in flames.
Four people, including children, were inside the home when the fire started.
All occupants made it out safely, but the blaze left their home inhabitable.
None of the firefighters were hurt putting out the fire.
Officials said they are looking into what caused it.